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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Diabetes Obes Metab. 2022 Sep 12;25(1):56–67. doi: 10.1111/dom.14843

Figure 1. Individual GIP and Dual GIP/GLP-1 Receptor Agonism on Choice Diet Preference between Chow and 40% High-Fat Diet (HFD) or Chow and 60% HFD for 5 Days in Mice.

Figure 1.

Effect of once daily injections [vehicle, GIP-085, or tirzepatide (TZP)] on daily intake of choice between chow (A) and 40% HFD (B) and in a separate group of mice choice between chow (C) and 60% HFD (D). Five-day cumulative intake of chow (E), intake of HFD (F), and body weight change (G) for both choice experiments. Daily average intake of chow and HFD as Kcals (H) and as a percentage of total Kcal intake (I) for both choice experiments. For panels E-I, comparisons made within a choice experiment are indicated with letter sets (a,b or x,z) and comparisons of the same treatment between choice experiment are indicated by asterisks. N=6–8 per treatment group.