Table 1.
Demographic and Clinical Characteristics of Participant Groups
HC Mean ± SD | CHR-P Mean ± SD | ESZ Mean ± SD | |
---|---|---|---|
| |||
Demographics | |||
Gender (% male) | 56.56 | 52.81 | 67.74 |
Age (Range: 12–35)a | 20.86 ± 6.36 | 18.68 ± 4.59 | 22.01 ± 4.56 |
Ethnicity (%) | |||
White / Caucasian | 58.19 | 56.18 | 51.61 |
Asian American | 20.49 | 13.48 | 22.58 |
Black / African American | 6.56 | 10.11 | 6.45 |
American Indian / Alaska Native | 2.46 | 2.25 | 0.00 |
Native Hawaiian / Pacific Islander | 1.64 | 3.37 | 2.15 |
More Than One Race | 10.66 | 10.11 | 11.83 |
Not Reported | 0.00 | 4.49 | 5.38 |
Medication (%) | |||
Chlorpromazine equivalents (mg) | --- | b c | 285.34 ± 322.97b |
Antipsychotic medication | --- | 14.61 | 80.65d |
(typical, atypical, unknown) | --- | (0, 100, 0) | (1.33, 94.67, 4.00) |
Symptom Severity Ratings e | |||
SOPS Positive | --- | 10.00 ± 4.88 | --- |
SOPS Negative | --- | 11.76 ± 5.78 | --- |
SOPS Disorganized | --- | 5.78 ± 3.89 | --- |
SOPS General | --- | 8.07 ± 4.82 | --- |
PANSS Positive | --- | --- | 13.78 ± 4.70 |
PANSS Negative | --- | --- | 16.55 ± 6.76 |
PANSS General | --- | --- | 32.94 ± 8.49 |
Note. HC=healthy control; CHR-P=clinical high-risk for psychosis; ESZ=early illness schizophrenia; SD=standard deviation; SES=socioeconomic status; SOPS=Scale of Psychosis-Risk Symptoms; PANSS=Positive and Negative Syndrome Scale.
Groups were significantly different on age, F(2,303)=9.05, p<.001, with the CHR-P group significantly younger than HC (p=.011) and ESZ (p<.001) groups.
Chlorpromazine equivalents for 11 CHR-P participants and 12 ESZ participants was missing.
Morphometric results showed the same pattern when medicated CHR-P patients were dropped.
Antipsychotic medication status for 7 participants missing.
SOPS Negative for 4 participants missing; SOPS Disorganized and General for 3 participants missing; PANSS scores only for UCSF participants.