Table 2.
Multivariable regression analysis for neonatal outcomes by endometrial thickness.
| Characteristics | Gestational age (weeks) | Non-adjusted β/OR | P-value | Adjusted β/OR | P-value |
|---|---|---|---|---|---|
| Adjust mean (95% CI) | (95% CI) | (95% CI) | |||
| Gestational age (week) | 0.07 (0.02, 0.12) | 0.0067 | 0.13 (0.03, 0.29) | <0.0001* | |
| Gestational age (EMT categorized into four groups) | |||||
| 6.00–8.90 mm (n = 378) | 38.60 ± 1.99 | Ref | Ref | ||
| 9.00–9.90 mm (n = 444) | 38.91 ± 1.68 | 0.22 (−0.01, 0.46) | 0.0659 | 0.29 (0.03, 0.48) | 0.0226* |
| 10.00–10.90 mm (n = 541) | 39.06 ± 1.52 | 0.32 (0.09, 0.55) | 0.0055 | 0.47 (0.15, 0.69) | 0.0019* |
| >11.00 mm (n = 647) | 39.17 ± 1.73 | 0.34 (0.12, 0.56) | 0.0021 | 0.55 (0.20, 0.83) | 0.0005* |
| P trend | <0.0001* | ||||
| Preterm (32–36 weeks) | 0.77 (0.63, 0.95) | 0.0129 | 0.55 (0.20, 0.75) | 0.0062* | |
| Preterm (EMT categorized into four groups) | |||||
| 6.00–8.90 mm (n = 378) | Ref | Ref | |||
| 9.00–9.90 mm (n = 444) | 0.66 (0.31, 1.41) | 0.2865 | 0.55 (0.13, 0.98) | 0.0451* | |
| 10.00–10.90 mm (n = 541) | 0.57 (0.26, 1.23) | 0.1512 | 0.42 (0.06, 0.87) | 0.0211* | |
| >11.00 mm (n = 647) | 0.26 (0.10, 0.65) | 0.0041 | 0.25 (0.04, 0.66) | 0.0034* | |
| Very preterm (<32 weeks) | 0.10 (0.01, 0.78) | 0.0287 | 0.37 (0.02, 1.44) | 0.6722 | |
| Birthweight (g) | 52.91 (27.77, 78.04) | <0.0001 | 19.11 (−2.48, 40.70) | 0.0832 | |
| Z-score | 0.03 (−0.03, 0.08) | 0.3333 | 0.03 (−0.03, 0.08) | 0.3750 | |
| LBW (<2500 g) | 0.60 (0.47, 0.77) | <0.0001 | 0.85 (0.55, 1.29) | 0.4411 | |
| Very LBW (<1500 g) | 0.19 (0.08, 0.47) | 0.0003 | 0.57 (0.01, 1.11) | 0.5997 | |
| Fetal macrosomia (≥4000 g) | 1.20 (0.97, 1.48) | 0.0982 | 1.22 (0.93, 1.61) | 0.1474 | |
| SGA (<10th percentile) | 0.86 (0.72, 1.03) | 0.1090 | 0.83 (0.67, 1.03) | 0.0922 | |
| Very SGA (<3rd percentile) | 0.76 (0.54, 1.09) | 0.1334 | 0.71 (0.44, 1.13) | 0.1434 | |
| LGA (>90th percentile) | 1.04 (0.86, 1.25) | 0.7138 | 1.14 (0.91, 1.42) | 0.2504 | |
| Very LGA (>97th percentile) | 0.93 (0.65, 1.33) | 0.6996 | 0.97 (0.63, 1.51) | 0.9101 | |
Analyses were adjusted for maternal age, paternal age, maternal BMI, basal FSH, anti-Müllerian hormone (AMH), type of infertility, prior gonadotropin cycle, ovarian stimulation protocols, dosage of gonadotropins, estrogen (E2) level on the hCG trigger day, number of oocytes retrieved, fertilization method, number and stage of embryos transferred, and gender of newborn; birthweight outcomes additionally adjusted for GA, preterm delivery (PTD), and very PTD.
LBW, low birthweight; LGA, large for gestational age; SGA, small for gestational age; OR, odds ratio; CI, confidence interval; Ref, reference group.
*
Statistically significant, with P < 0.05.