Fig. 5.

Contribution of glycolysis and oxidative phosphorylation to the metabolic activity of spleen CD4+ T cells from either uninfected or S. aureus-infected mice upon stimulation with anti-CD3/anti-CD28 antibodies. Metabolic dependence on glycolysis (cyan bars) or oxidative phosphorylation (purple bars) of spleen CD4+ T cells isolated from uninfected (a) or S. aureus-infected (b) mice upon stimulation with anti-CD3/anti-CD28 antibodies. Metabolic dependence was determined as described in the “Materials and methods” section. Each bar shows the mean ± SD of five independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001