Table 2.

Adjusted hazard ratios of SBP levels on transition probabilities by multistate modeling

	Baseline → CV event	Baseline → Death	CV event → Death
SBP levels, mmHg
No medication
<110	0.91 (0.71,1.16)	1.00 (0.93,1.07)	0.89 (0.65,1.22)
110~129	0.89 (0.64,1.25)	1.19 (1.09,1.29) **	1.13 (0.74,1.73)
130~149	ref	ref	ref
≥150	1.23 (0.77,1.97)	1.23 (1.08,1.40) *	1.16 (0.64,2.12)
1 or 2 medications
<110	1.24 (1.12,1.37) **	1.04 (0.99,1.08)	0.93 (0.82,1.07)
110~129	1.74 (1.51,1.99) **	1.30 (1.21,1.39) **	1.16 (0.96,1.40)
130~149	ref	ref	ref
≥150	1.14 (0.96,1.34)	1.06 (0.98,1.14)	1.00 (0.80,1.25)
≥3 medication
<110	1.14 (1.02,1.28) *	1.05 (0.97,1.15)	1.19 (1.02,1.39) *
110~129	1.56 (1.31,1.84) **	1.39 (1.21,1.59) **	1.10 (0.86,1.42)
130~149	ref	ref	ref
≥150	0.98 (0.83,1.16)	1.11 (0.99,1.25)	0.98 (0.79,1.23)

Notes: Data are hazard ratios (95% confidence intervals). SBP, systolic blood pressure. Reference group was SBP of 130~149mmHg. Models adjusted for age, sex, race, height, weight, smoking status, cardiovascular disease, heart failure, and activities of daily living (model 1).

^*P-value<.05

^**P-value <.001