. Author manuscript; available in PMC: 2024 Aug 1.

Published in final edited form as: Am J Ophthalmol. 2023 Feb 21;252:213–224. doi: 10.1016/j.ajo.2023.02.013

Table 1:

Breakdown of optic neuritis outcomes after plasma exchange based on etiology

Etiology	Median Age (range)	Female %	Median weeks to PLEX	Median VA at time of PLEX	Median Final VA	% 20/200 or worse
AQP4+NMOSD (n=75)	45.5 (16–75)	81%	3 (IQR, 2–4.4)	1.7 (CF) (IQR, 1–2)	0.18 (20/30) (IQR, 0–1.3)	30.6%
MOGAD (n=92)	36 (11–72)	60%	2.3 (IQR, 1–3.6)	1.7 (CF) (IQR, 0.9–2)	0.00 (20/20) (IQR, 0–0.1)	1%
Multiple sclerosis (n=108)	33.5 (16–65.2)	72%	2.9 (IQR, 1.8–4)	1.7 (CF) (IQR, 1–2)	0.10 (20/25) (IQR, 0–0.8)	24%
Idiopathic (n=83)	39 (17–66)	61%	2 (IQR, 1.5–4.5)	1.7 (CF) (IQR, 1–2)	0.10 (20/25) (IQR, 0–0.8)	23%

Abbreviations: plasma exchange (PLEX), visual acuity (VA), aquaporin-4 IgG positive neuromyelitis optica spectrum disorder (AQP4+NMOSD), myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), interquartile (IQR)