Table 3.

Results of Cox regression models (hazard ratios) and age, sex and race-adjusted incidence rates (per 100 person-years); estimates and 95% confidence intervals. Kaiser Permanente Northern California Diabetes and Aging Study 2015 Cohort.

Outcome	Class 1 (healthy) Risk(95% CI)	Class 2 (geriatric) Risk(95% CI)	Class 3 (cardiac) Risk(95% CI)	HR (Class 2/ Class 1)	HR (Class 3/ Class 1)
Microvascular Complications	0.9 (0.9, 1.0)	1.3 (1.3, 1.4)	6.3 (6.1, 6.5)	1.43 (1.33, 1.53)	6.09 (5.79, 6.41)
Cardiovascular Complications	1.6 (1.6, 1.7)	2.2 (2.2, 2.3)	6.5 (6.3, 6.6)	1.39 (1.32, 1.46)	3.97 (3.80, 4.14)
Infection	2.7 (2.6, 2.7)	5.0 (4.9, 5.2)	9.7 (9.5, 10.0)	1.90 (1.83, 1.97)	3.68 (3.56, 3.81)
Hypoglycemia	0.7 (0.7, 0.8)	1.2 (1.1, 1.2)	2.1 (2.0, 2.2)	1.64 (1.52, 1.77)	2.93 (2.74, 3.13)
Hyperglycemia	0.3 (0.3, 0.3)	0.5 (0.4, 0.5)	0.6 (0.6, 0.7)	1.63 (1.45, 1.83)	2.19 (1.96, 2.46)
Mortality	2.3 (2.3, 2.4)	3.8 (3.6, 3.9)	8.0 (7.8, 8.2)	1.63 (1.57, 1.70)	3.56 (3.45, 3.68)
Combined non-mortality	5.4 (5.3, 5.5)	9.0 (8.8, 9.3)	21.3 (20.9, 21.7)	1.65 (1.60, 1.70)	3.74 (3.65, 3.84)
Combined outcome	6.7 (6.6, 6.8)	11.1 (10.9, 11.4)	24.6 (24.1, 25.0)	1.64 (1.60, 1.69)	3.54 (3.45, 3.62)

All of the p-values for testing the null hypothesis that the three classes are equivalent were < 0.0001.