Table 1.
Baseline Patient Demographics and Clinical Characteristics.
| Characteristic | 8-year timepoint slope of eGFR (n=165) | 20-year timepoint KF (n=125) |
|---|---|---|
| Sex | ||
| Female | 61% | 60% |
| Male | 39% | 40% |
| Height (cm), median (IQR) | 170 (164–181) | 172 (164–182) |
| Age (yo), median (IQR) | 34 (26–40) | 35(27–40) |
| BMI (kg/m 2 ), median (IQR) | 24 (22–28) | 25(22–29) |
| Race | ||
| Caucasian | 87% | 92% |
| African American | 10% | 6% |
| Asian, Hispanic, and Native American | 3% | 2% |
| eGFR (ml/min/1.73m 2 ), median (IQR) | 92 (80–110) | 89 (77–108) |
| Genotype + effect | ||
| PKD1 truncating | 58% | 57% |
| PKD1 non-truncating | 22% | 26% |
| PKD2 truncating | 11% | 10% |
| PKD2 non-truncating | 2% | 2% |
| GANAB non-truncating | 1% | 1% |
| Not available | 6% | 4% |