Table 3.
Summary statistics for baseline age and imaging biomarkers in predicting the progression to kidney failure after a 20-year follow-up period.
| Biomarker | median (IQR) | median (IQR) | P-valuea | sensitivity | specificity | cut-off point | Az (95% CI) | ht-TKV Az P-value b |
|---|---|---|---|---|---|---|---|---|
| 20yr KF | Yes (n=71) | No (n=54) | ||||||
| Age | 35.43 (30–40.19) | 31.73 (25.01–38.28) | 0.0333 | 0.83 | 0.39 | 27.76 | 0.61 (0.51–0.71) | 0.0003 |
| ht-TKVp | 807.37 (559.12–1109.8) | 419.58 (309.6–623.38) | <0.0001 | 0.87 | 0.65 | 457.55 | 0.81 (0.72–0.88) | - |
| ht-TCV | 372.7 (232.46–597.4) | 131.49 (81.6–329) | <0.0001 | 0.79 | 0.72 | 212.12 | 0.78 (0.69–0.87) | 0.0206 |
| ht-RPV | 403.99 (316.77–548.97) | 283.43 (236.43–309.71) | <0.0001 | 0.82 | 0.78 | 311.78 | 0.83 (0.75–0.89) | 0.3233 |
| TCN | (274–577) | (125.75–261.5) | <0.0001 | 0.73 | 0.85 | 307 | 0.86 (0.78–0.91) | 0.0791 |
| CPSA | 14.71 (9.06–20.68) | 5.64 (3.93–8.09) | <0.0001 | 0.82 | 0.80 | 8.51 | 0.86 (0.79–0.92) | 0.027 |
a
Wilcoxon rank sum test
b
DeLong test
Units: Age (yo), ht-TKV (ml/m), ht-TCV (ml/m), ht-RPV (ml/m), TCN (cyst unit), CPSA (dm2)