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. Author manuscript; available in PMC: 2023 Jul 23.
Published in final edited form as: Brain Behav Immun. 2023 May 5;111:298–311. doi: 10.1016/j.bbi.2023.04.013

Figure 5.

Figure 5.

Intrathecal rat ACS (rCS) treatment inhibits glial reaction in the spinal cord dorsal horn of male mice with CIPN. (A,B) Double immunofluorescence staining of the lumbar spinal dorsal horn sections showing GFAP and IBA1 immunostaining following rNCS (A) and rCS treatment (B) in PTX mice. (C-D) Quantification of the integrated density of GFAP (C) and IBA1 (D) in the lumbar spinal dorsal horn of PTX mice treatment with rNCS and rCS (n = 5/group). *p< 0.05, **p< 0.01 vs. control serum (rNCS). Unpaired two-tailed Student’s t test. Spinal cord tissues were harvested one week after the rCS treatment. Male donors and receivers were tested.