Figure 8.
Nanoparticle tracking analysis showing increased exosome concentration in male rat CS (rCS). (A) Paradigm of nanoparticle tracking analysis. (B) Size distribution and concentrations of extracellular vesicles in rNCS, rCS, and U-rCS in each of five rats and all rats combined. (C) Particle density per mL serum. (D) Normalized extracellular vesicle (EV) concentrations as percentage of rNCS. **p<0.01, ***p<0.001, n=5 rats, one-way ANOVA, followed by Bonferroni posthoc test. rUCS, rat CS after ultracentrifugation. Note that EV is deleted in rUCS.