Table 2A.

Associations with brain volumes. Results are based on regression models. All outcomes are standardized values (z-scored) residualized for total cranial volume. Age treated linearly.

	Total brain volume Estimates [95% CI]	Hippocampus Estimates [95% CI]	Log lateral ventricle Estimates [95% CI]	Log WMH Estimates [95% CI]
Female	ref	ref	ref	ref
Male	−0.186^b [−0.326;−0.045]	0.078 [−0.133;0.289]	0.251^c [0.107;0.395]	0.159 [−0.004;0.321]
Age	−0.062^c [−0.068;−0.057]	−0.022^c [−0.028;−0.016]	0.046^c [0.040;0.053]	0.043^c [0.038;0.048]
Height	−0.004 [−0.012;0.004]	−0.003 [−0.013;0.007]	−0.003 [−0.012;0.007]	−0.006 [−0.014;0.002]
Dominican	ref	ref	ref	ref
Central American	−0.157 [−0.340;0.027]	0.052 [−0.141;0.245]	−0.016 [−0.217;0.185]	−0.498^c [−0.722;−0.274]
Cuban	−0.245^b [−0.420;−0.071]	−0.042 [−0.263;0.179]	0.086 [−0.115;0.287]	−0.434^c [−0.623;−0.246]
Mexican	−0.193^a [−0.350;−0.035]	0.039 [−0.130;0.208]	−0.123 [−0.285;0.040]	−0.593^c [−0.761;−0.425]
Puerto-Rican	−0.310^b [−0.514;−0.106]	−0.172 [−0.377;0.034]	0.190 [−0.013;0.393]	0.118 [−0.072;0.307]
South American	−0.110 [−0.348;0.128]	−0.042 [−0.316;0.232]	−0.048 [−0.318;0.221]	−0.475^c [−0.692;−0.258]
Mixed/Other	−0.105 [−0.581;0.371]	0.414 [−0.042;0.871]	0.142 [−0.147;0.431]	−0.074 [−0.352;0.203]
Intercept	4.839^c [3.407;6.272]	1.838^a [0.273;3.403]	−2.666^b [−4.463;−0.869]	−1.477^a [−2.799;−0.154]

Key: CI, confidence interval; WMH, white matter hyperintensities.

= p < 0.05

= p < 0.01,

= p < 0.001