Table 1.

LD-TMAc targeted residues on bCAII

Probe	Label Site	Modification %	SASA %
1†	His3	95 ± 4	81
	His63	50 ± 20	17.3
2†	His3	70 ± 20	81
	His63	60 ± 30	17.3
	Ser181#	0.3 ± 0.2	30
	Ser171/Thr172	0.09 ± 0.08	31.5$
	Lys166*	0.06 ± 0.07	29.3
3‡	His3	80 ± 30	81
	His63	70 ± 10	17.3
	Ser72#	30 ± 1	74.8
	His2*	2 ± 2	11.3
	Ser28*	1 ± 0.5	0
	Ser64*	0.5 ± 0.4	0.2
	Ser171/Thr172	0.3 ± 0.1	31.5$
	Lys250	0.2 ± 0.03	29.2
	Lys44	0.1 ± 0.04	66.3

^†Based on 6 replicates.

^‡Based on 3 replicates.

^$Ser171 and Thr172 average.

^#An outlier replicate removed at at 95% confidence.

^*Statistically significant at 90% confidence. The rest of the data is statistically significant at 95% confidence.