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. 2023 Jul 19;18:3973–3988. doi: 10.2147/IJN.S413496

Table 1.

Application of Exosome Delivery Drug in the Treatment for Pancreatic Cancer

Origin Delivery of Substances Cancer Type Result Reference
Autologous Gemcitabine PC Significantly inhibited tumor growth [60]
PC derived siPAK4 PC Inhibited tumor growth and prolong survival [61]
Macrophage-derived Gemcitabine, antagomiR-365 PDAC Overcame drug resistance and improved survival rate [62]
Bone marrow mesenchymal stem cell Galectin-9, siRNA PC Induction of anti-tumor immunity [63]
Bone marrow mesenchymal stem cell Gemcitabine, Paclitaxel PDAC Overcame drug resistance [64]
Tumor derived re-assembled Chlorin e6 PC Inhibition of tumor growth and metastasis [65]