Table 1.
Application of Exosome Delivery Drug in the Treatment for Pancreatic Cancer
Origin | Delivery of Substances | Cancer Type | Result | Reference |
---|---|---|---|---|
Autologous | Gemcitabine | PC | Significantly inhibited tumor growth | [60] |
PC derived | siPAK4 | PC | Inhibited tumor growth and prolong survival | [61] |
Macrophage-derived | Gemcitabine, antagomiR-365 | PDAC | Overcame drug resistance and improved survival rate | [62] |
Bone marrow mesenchymal stem cell | Galectin-9, siRNA | PC | Induction of anti-tumor immunity | [63] |
Bone marrow mesenchymal stem cell | Gemcitabine, Paclitaxel | PDAC | Overcame drug resistance | [64] |
Tumor derived re-assembled | Chlorin e6 | PC | Inhibition of tumor growth and metastasis | [65] |