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. 2023 Jul 19;18:3913–3935. doi: 10.2147/IJN.S417855

Table 3.

Properties of General Anesthetic Nanomedicines

Nanomedicine Particle Size Carrier Material Effect References
Propofol nanoparticles 180±1.2 nm Octanol-alginate nanoparticles [82]
Propofol nanodroplets 317.6±148.2 nm Polyethylene glycol-b-polycaprolactone and perfluorocarbon Ultrasound can double the rate of drug release [83]
Propofol loaded propionylated amylose helix 55 ± 12 nm Propionylated amylose helix The induction time was 0.22 times of that the propofol emulsion group;
The recovery time was 0.20 times that of the propofol emulsion group
[84]
PROP- GQY, ET-GQY, ET26-GQY 165.6±11.93nm Peptide GQY GQY can be used as a high loading fat-free carrier material [85]
126–138 nm Hemifluorinated dibranched polymers [86]
Propofol-LCNP ≈200m Self-assembled lipid liquid crystalline [87]
Eto-SOPM 109.23±0.81nm Poloxamer micelles The rats recovered from the loss of righting reflex 10% faster than the free group [88]
ETM-ILE 168.0±0.3nm Lipid [89]

Abbreviations:GQY, Gly-Gln-Tyr; PROP, propofol; ET, etomidate; ET26, an analog of etomidate; LCNP, Liquid crystalline nanoparticles; Eto-SOPM, etomidate-loaded poloxamer micelles; ETM-ILE, etomidate intravenous lipid emulsion.