Fig. 3.

Prevention efficacy (PE) of VRC01 concentrations against HIV-1 acquisition as a function of VRC01 concentration at exposure (top x-axis) and of average predicted PT₈₀neutralization titre at exposure (bottom x-axis). Shaded area provides 95% pointwise confidence intervals. Prevention efficacy at a given level of VRC01 concentration or PT₈₀ was estimated via Cox regression models by pooled treatment group and dose. The geometric mean IC₈₀ used to convert VRC01 concentration to PT₈₀ was 6.8 μg/ml.