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. 2023 Jun 9;64:102782. doi: 10.1016/j.redox.2023.102782

Fig. 7.

Fig. 7

MiR-335 caused oxidative stress in RVLM of SIH rats via targeting Lig3. (A–C) Effects of miR-335 downregulation on the level of 8-OH-dG and activities of SOD and CAT in RVLM of SIH rats were reversed by Lig3 depletion. (D) Lig3 knockdown weakened the suppressive influence of miR-335 silencing on ROS production in RVLM of SIH rats. Data were expressed as mean ± SEM. Statistical significance was determined by one-way ANOVA, followed by post-hoc Bonferroni test (A–D). n = 6 rats per group (A–D). *p < 0.05, **p < 0.01, ***p < 0.001, and ns means nonsignificant versus SIH group.