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. 2023 Jun 30;64:102805. doi: 10.1016/j.redox.2023.102805

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© 2023 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 7 — Systematic model showing (1) epigenetic regulation of MT biosynthesis, (2) transcriptional regulation of MT and SA through heat shock factors (HSFs), and (3) fine-tuning of ASMT2/PR1-related activity. HDA9: HISTONE DEACETYLATION 9; HSP 90: Heat Shock Protein 90; PBS3: AVRPPHB SUSCEPTIBLE3; PP2C1/12: protein phosphatase; MT: melatonin; SRS1: SHI-related sequence; TDC2: tryptophan decarboxylation 2; T5H: tryptamine-5-hydroxylase; ASMT2: N-acetylserotonin O-methylthransferase 2, PR1: pathogenesis-related protein 1.