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. 2023 May 29;14:100219. doi: 10.1016/j.lansea.2023.100219

Table 2.

Outcome measures.

PS group (n = 121) CPAP group (n = 123) Difference, PS minus CPAP (95% CI) p value
Primary outcome
 Successful extubation after first SBT n (%) 97 (80.2) 93 (75.6) 4.6 (−5.8, 15) 0.39
Secondary outcomes
 First SBT pass n (%) 111 (91.7) 105 (85.4) 6.3 (−1.6, 14.3) 0.12
 Interval between first SBT and extubation (hours) 2 (1.5, 4) 2 (1, 3.5) 0.24 (−0.13, 0.62) 0.15
 Reintubation within 72 h n (%) 14 (11.6) 12 (9.8) 1.8 (−5.9, 9.6) 0.65
 Time to re-intubation (hours) 24 (15.5, 36) 18 (6.75, 58) −6.2 (−23.2, 10.8) 0.98
 Need for post extubation respiratory support n (%) 52 (43) 49 (40) 3.1 (−9.2, 15.5) 0.62
 Reason for post-extubation respiratory support n (%)
 Decided a priori 23 (19) 15 (12) 6.8 (−2.3, 15.9) 0.14
 Increased work of breathing 23 (19) 23 (19) 0.3 (−9.5, 10.1)
 Upper airway obstruction 3 (2.5) 3 (2.5) 0 (−3.8, 3.9)
 Cardiac dysfunction 1 (1) 2 (1.5) −0.8 (−3.6, 2)
 Neurological/neuromuscular reasons 2 (1.5) 6 (5) −3.2 (−7.7, 1.2)
 Successful extubation after 2nd SBT n (%) 10 (8.3) 17 (13.8) −5.5 (−13.4, 2.3) 0.17
 All reintubations at any point in time n (%) 17 (14) 18 (14.6) −0.6 (−9.4, 8.2) 0.90
 Tracheostomy n (%) 6 (5) 3 (2.5) 2.5 (−2.2, 7.3) 0.30
 Length of invasive ventilation (days) 5.5 (3, 7) 5 (3.5, 7) 0.1 (−1.3, 1.5) 0.96
 Length of PICU stay (days) 9 (6, 15) 8 (5.5, 13) 1 (−1, 3) 0.48
 Length of hospital stay (days) 16 (10, 25) 16 (10, 22) 1.9 (−0.9, 4.7) 0.56
 Unfavourable outcome n (%) 0 (0) 4 (3.3) −3.3 (−6.4, −0.1)
 Death 0 (0) 1 (0.8)
 Discontinued care 0 (0) 3 (2.5)

Values are expressed in numbers (%) or median (interquartile range).