Table 1.
Clinical characteristic of the WellGen according to sex.
| Characteristic | WellGen study (n = 2217) |
NGT (PMNS, n = 461) |
|||||
|---|---|---|---|---|---|---|---|
| Male | Female | All | Male | Female | All | p value | |
| No. of participants (%) | 1224 (55.2) | 993 (44.8) | 2217 | 173 (37.5) | 288 (62.5) | 461 | |
| Age, yearsa | 42.04 (9.58) | 41.88 (10.25) | 41.97 (9.88) | 39.80 (4.21) | 33.31 (3.29) | 35.56 (4.80) | 1.35E-31 |
| BMI, kg/m2 | 25.46 (3.68) | 27.27 (4.45) | 26.27 (4.14) | 21.16 (3.39) | 19.74 (2.99) | 20.25 (3.21) | 8.59E-192 |
| Fasting glucose, mg/dL | 8.79 (3.15) | 9.04 (3.32) | 8.91 (3.23) | 4.92 (0.45) | 4.79 (0.36) | 4.84 (0.40) | 3.39E-141 |
| HbA1c, mmol/mol | 71.88 (22.59) | 71 (22.62) | 71.48 (22.6) | – | – | – | – |
| HbA1c, % | 8.73 (2.07) | 8.65 (2.07) | 8.69 (2.07) | – | – | – | – |
| Fasting C-peptide, nmol/l | 0.82 (0.48) | 0.83 (0.48) | 0.83 (0.48) | – | – | – | – |
| HOMA2-B | 64.81 (44.3) | 64.06 (46.17) | 64.48 (45.14) | 82.24 (36.67) | 85.22 (32.94) | 84.14 (34.33) | 1.69E-45 |
| HOMA2-IR | 2.2 (1.38) | 2.24 (1.35) | 2.22 (1.37) | 0.78 (0.51) | 0.79 (0.44) | 0.78 (0.47) | 7.24E-57 |
Values are mean (SD).
p-values are calculated using ANOVA (unequal variances) adjusted for age and sex.
NGT: Normal glucose tolerance, PMNS: Pune Maternal Nutrition Study.
a
Age at diabetes diagnosis for WellGen, age at study for PMNS.