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. 2023 Jul 23;19(8):67. doi: 10.1007/s11306-023-02031-9

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Depiction of the metabolites/enzymes involved in glutamine metabolism that can be measured by biochemical assays. CoA coenzyme-A, Cit citrate, ICT isocitrate, IDH isocitrate dehydrogenase, α-KG α-ketoglutarate, KGDHC α-ketoglutarate dehydrogenase complex, SuccCoA succinyl-CoA, SCS succinyl-CoA synthesize, Succ succinate, SDH succinate dehydrogenase, Fum fumarate, Mal malate, MDH malate dehydrogenase, OAA oxaloacetate, CS citrate synthesize, Glu glutamate, GLS glutaminase, GDH glutamate dehydrogenase