Fig. 1. Diversity-oriented synthesis of structurally diverse monodentate biaryl phosphines containing both P- and axial chirality.
a Monodentate biaryl phosphines with various chiral elements. b Transition-metal catalyzed achiral alkynylation of the C–P bond. c Enantioselective C–P bond arylation (our previous work). d Diversity-oriented synthesis of structurally diverse P- and axially chiral monodentate biaryl phosphines (this work).