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. 2023 Jul 23;13:11893. doi: 10.1038/s41598-023-38963-4

Table 3.

Antifungal activity of selected derivatives against clinical strains in comparison with C. albicans ATCC 10231.

Compound *MIC90 µg mL−1
Candida albicans ATCC 10231 Candida albicans B3 Candida albicans B4 Candida albicans Gu4 Candida albicans Gu5 Candida albicans F2 Candida albicans F5
3 16 16 32 16 32 16 32
5 16 64 64 64 64 32 64
6 16 16 64 16 64 32 32
7 16 32 64 32 32 32 32
8 32 32 32 32 32 32 32
9 4 8 8 8 8 8 8
12 8 64 64 64 64  > 64  > 64
13 8 16 16 16 16 16 16
14 8 16 16 8 8 8 8
15 8 8 8 8 8 8 8
42 8 8 8 8 8 8 8
44 4 4 4 4 4 4 4
45 32 64 64 64 64 64 64
Fluconazole 8 1 16 4  > 64 8  > 64

* > Means no activity at the concentration mentioned. In this assay, the MIC90 value of fluconazole was recorded as a positive control. The experiments were performed at least in three replicates.