Table 2.

Proportions of different cells in imprint smears of internal organs of rats exposed to copper oxide nanoparticles at different dose levels (X̅ ± Sx).

Cells observed	Controls	Exposure group 1	Exposure group 2
Degenerated hepatocytes in liver smears, %	5.33 ± 0.42	8.33 ± 0.67 *	11.00 ± 0.632 *#
Degenerative cells of proximal tubules in kidney smears, %	6.33 ± 0.49	14.17 ± 0.75 *	14.67 ± 0.49 *
Degenerative cells of distal tubules in kidney smears, %	5.00 ± 0.58	6.17 ± 0.48	6.67 ± 0.33 *
Eosinophils in kidney smears, %	2.67 ± 0.33	4.83 ± 0.31 *	4.33 ± 0.42 *

Significant values are in [bold].

p < 0.05 compared with * controls and # exposure group 1.