Table 5.

Indicators of genetic alterations under effect of copper oxide nanoparticles at different dose levels (X̅ ± Sx).

Indicator		Control	Exposure group 1	Exposure group 2
Level of expression of genes encoding NMDA receptor subunit proteins in the hippocampus	GRIN1, GluN1 subunit proteins	1.1 ± 0.078	0.46 ± 0,077	0.101 ± 0.06*
	GRIN2A, GluN2A subunit proteins	1.17 ± 0.361	0.693 ± 0,08	0.497 ± 0.13 *
	GRIN2B, GluN2B subunit proteins	1.18 ± 0.795	0.642 ± 0,1	0.343 ± 0.05 *
Genomic DNA fragmentation factor for nucleated blood cells		0.425771 ± 0.00002	0.399505 ± 0.00022*	0.398725 ± 0.00036*

Significant values are in [bold].

*p < 0.05 compared with controls.