Figure 2.
Hazard ratios for recurrent atherosclerotic cardiovascular events associated with 1 standard deviation higher log-transformed Lp(a) within subgroups.
Abbreviations: ACR, albumin-creatinine-ratio; CHD, coronary heart disease; CI, confidence interval; eGFR, estimated glomerular filtration rate; HR, hazard ratio; hs-CRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein; Lp(a), lipoprotein(a); PAD, peripheral artery disease; SD, standard deviation.
Recurrent atherosclerotic cardiovascular events include myocardial infarction hospitalization, ischemic stroke hospitalization, PAD hospitalization, CHD death, or ischemic stroke death.
The SD of log-transformed Lp(a) was equal to 1.3 units, which represents a 3.7 times increase in Lp(a) levels in their original scale.
All hazard ratios were adjusted for age, sex, race/ethnicity, Chronic Renal Insufficiency Cohort study center, education, income, smoking status, physical activity, body mass index, diabetes, systolic blood pressure, antihypertensive medication use, eGFR, high-density lipoprotein cholesterol, triglycerides, high-sensitivity C-reactive protein, albumin-creatinine ratio, fibroblast growth factor 23, homocysteine, use of aspirin and statins, and non-Lp(a) LDL cholesterol.