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Congenital Generalized Lipodystrophy diagnosis criteria.
| Major criteria |
| Insulin resistance |
| Loss of subcutaneous fat affecting both trunk and limbs |
| Acromegaloid features |
| Hepatomegaly |
| Hypertriglyceridemia |
| Minor criteria |
| Early onset of puberty in females |
| Mental retardation |
| Hypertrophic cardiomyopathy |
| Hypertrichosis |
| Prominent veins |
| Bone cysts |
| Diagnosis |
| Presence of 3 major criteria OR 2 Major with ≥2 Minor criteria AND/OR Identification of mutation on CGL linked genes |
