Table 1.
Nest-building, quantified before (Pre) and after (Post) daily icv injections of vehicle or OTA (started on gestation day 29)
| Group A | Digging (g; median±iqr)& | Straw-carrying (g; median±iqr)& |
Hair-pulling (% females) |
|||
|---|---|---|---|---|---|---|
| Pre* | Post | Pre* | Post | Prea | Postb | |
| Primiparous-VEH (n=6) |
126 (20, 261) |
ND |
35 (12, 63) |
ND | 33.3% | 66.6% |
| Primiparous-OTA (n=26) |
ND | ND | 30.7% | 65.4% | ||
| Multiparous-VEH (n=13) |
351 (191, 420) B |
ND |
20 (6, 42) |
ND | 7.6% | 53.8% |
| Multiparous-OTA (n=2) |
ND | ND | ND | ND | ||
values obtained on gestation days 21, 25, 27, and 28 were added to give a single number for each experimental animal during the “pre” phase
“Pre” values for digging and straw-carrying were combined, in primiparous and multiparous groups, to include both VEH and OTA animals, as does had not yet been given any icv injections. Thus, n=32 and n=15, respectively
determined on gestation day 28
determined on gestation day 30
ND=not determined because OTA (or VEH) injections began on gestation day 29 and, by that time, digging and straw-carrying had already occurred.
Number of does shown in each group corresponds to those mothers from which we were able to quantify digging, straw-carrying or hair-pulling
DF=3, F=4.996, p=0.005