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. 2022 Aug 5;10(5):2167–2178. doi: 10.1016/j.gendis.2022.07.006

Figure 1.

Fig. 1

JAG1 was closely related to the malignant phenotype of TNBC. (A) The expression of the Notch signaling pathway in different breast cancer cell lines was detected by the qRT-PCR assay. (B) The expression of JAG1 in different breast cancer subtypes was analyzed by UALCAN database. (C) The correlation between JAG1 and the survival of breast cancer patients was analyzed by the Kaplan–Meier Plotter database. (D) The tumor volume in nude mice with injection of 231 and 231B into the mammary pad. (E) Tumors in situ and liver metastasis in nude mice. (F) HE staining for tumors in situ and liver metastasis. ns means “Not statistically significant” (P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001).