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. 2022 Aug 5;10(5):2167–2178. doi: 10.1016/j.gendis.2022.07.006

Figure 5.

Fig. 5

Exosomal MALAT1 promotes the angiogenesis of HUVEC through a cascade of miR-140-5p/JAG1/VEGFA signals. (A) Screening MALAT1-related miRNAs in breast cancer by Venn diagram. (B) qRT-PCR to verify the knockdown efficiency of the three interference fragments. (C) qRT-PCR to detect the expression of miR-140-5p in HUVEC. (D) KEGG pathway analysis of miR-140-5p. (E, F) qRT-PCR to detect JAG1 (E) and VEGFA (F) expression (P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001).