Figure 5.
Exosomal MALAT1 promotes the angiogenesis of HUVEC through a cascade of miR-140-5p/JAG1/VEGFA signals. (A) Screening MALAT1-related miRNAs in breast cancer by Venn diagram. (B) qRT-PCR to verify the knockdown efficiency of the three interference fragments. (C) qRT-PCR to detect the expression of miR-140-5p in HUVEC. (D) KEGG pathway analysis of miR-140-5p. (E, F) qRT-PCR to detect JAG1 (E) and VEGFA (F) expression (∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001).