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. 2022 Aug 6;10(5):2125–2136. doi: 10.1016/j.gendis.2022.06.010

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© 2022 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — CHPF knockdown inhibited tumor growth of osteosarcoma in vivo. (A) A nude mice model of CHPF knockdown was constructed. (B) The photos of tumors removed from mice models were collected. (C–E) The fluorescence (C), volume (D) and weight (E) of xenograft tumors were measured. (F) The patterns of CHPF and Ki-67 were detected by IHC analysis in tumor sections from the mice models. The data were expressed as mean ± SD (n ≥ 3). ∗P < 0.05.