Figure 5.

Fluorescence imaging of BC-3 in xenografted mouse models and clinical BC tissue samples. (A) BC-bearing xenografted mice were intravenously injected with Cy5-labeled BC-3 (upper panel) or Cy5-labeled Library (lower panel). Fluorescence images were taken at different time points by an in vivo imaging system. (B) BC tissues and normal tissues at different stages were incubated with Cy5-labeled BC-3 or Library. Fluorescence signals were detected with panoramic scans (scale bar = 400 μm). (C) Summary statistics of the relative fluorescence intensity of normal bladder and BC tissues (Comparison: Normal tissues vs. Cancer tissues: ∗P < 0.05).