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The pyocyanin synthesis pathway regulatory network of P. aeruginosa. (Left panel) The pyocyanin synthesis regulatory network is mediated by 19 regulators (PhoB, PA3249, PA1315, PA0784, GacA, CarR, PqsE, AmrZ, QscR, QteE, RhlR, RsaL, LasR, BfmR, CzcR, RpoS, PrtR, AlgR and RsmA/N) and three co-target genes (amrZ, phzA1-G1 and phzA2-G2). (Right panel) The biosynthesis pathway of phenazines (including pyocyanin, 1-hydroxyphenazine and phenazine-1-carboxylic acid).
