Table 1.
Baseline characteristics and clinical parameters of the study population.
| Healthy subjects (n=41) | Lung Qi Deficiency COPD (n=65) | Lung-kidney Qi Deficiency COPD (n=52) | Lung-spleen Qi Deficiency COPD (n=54) | P-value | |
|---|---|---|---|---|---|
| Age, years | 55 (50-65) | 61 (42-75) | 64 (45-74) | 64 (44-74) | <0.001 |
| Sex, % male | 25 (60.98%) | 50 (76.92%) | 40 (76.92%) | 43 (79.63%) | 0.192 |
| Body mass index | 24.76 (14.69-31.55) | 24.61 (17.83-31.25) | 23.58 (16.16-30.92) | 23.46 (17.72-29.99) | 0.698 |
| Current smoker, % | 15 (36.59%) | 38 (58.46%) | 26 (50%) | 32 (59.26%) | 0.104 |
| Course of COPD, months | 0 | 48 (1-516) | 84 (6-360) | 60 (1-245) | <0.001 |
| FVC(L) | 3.61 (2.15-5.43) | 2.61 (0.91-3.42) | 2.2 (0.71-5.28) | 2.4 (1.11-4.32) | <0.001/<0.001* |
| FEV1(L) | 2.61 (1.96-3.84) | 1.58 (0.5-2.19) | 1.4 (0.79-3.07) | 1.33 (0.47-2.87) | <0.001/0.034* |
| FEV1/FVC (%) | 78.92 (70.71-91.16) | 60.61 (21.07-216.08) | 50.00 (27.01-197.18) | 25.24 (17-75.46) | <0.001/0.015* |
Baseline characteristics were expressed as median (interquartile range) or n (%).
P<0.05 was considered statistically significant.
†P-values were calculated by the ANOVA test for continuous variables or the chi-squared test for categorial variables.
* P-values of ANOVA test between the groups of three COPD TCM patterns.