Figure 6.
LRP1B directly binds to NCSTN and regulates the PI3K/AKT/mTOR pathway. (A)LRP1B knockdown causes upregulation of the PI3K/AKT pathway. (B)LRP1B overexpression inhibited the PI3K/AKT pathway. (C)LRP1B regulates the PI3K/AKT/mTOR pathway. (D) Immunoprecipitation (IP) assay in Huh7 cells. (E) IP assay in 293 T cells using a primary antibody specific for HA. (F) IP was performed with a primary antibody specific for Flag.