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. 2023 Jul 10;11:1220405. doi: 10.3389/fcell.2023.1220405

TABLE 1.

Human pannexin1 (Panx1) proteins are widely expressed. Panx1 proteins can be found in the brain, skin, lung, eye, breast, gastrointestinal tract, urinary system, reproductive system and blood cells.

Organ system Tissue or cell type Reference(s)
Nervous system Cortical tissue Dossi et al. (2018)
Glioblastoma cells Wei et al. (2015)
Eye Žužul et al. (2022)
Corneal tissue Cui et al. (2016)
Integumentary system Skin and adnexal structures Cowan et al. (2012)
Epidermal sensory cells Cárcaba et al. (2022)
Breast epithelial cells Jalaleddine et al. (2019)
Digestive system Liver tissue Leroy et al. (2022), Wang et al. (2022)
Hepatocytes Wang et al. (2022)
Colon segments Diezmos et al. (2013)
Pancreatic islets Bartley et al. (2019)
Colonic carcinoma cells Alhouayek et al. (2019)
Gastric carcinoma cells Ying et al. (2021)
Respiratory system Lung tissue Luu et al. (2021)
Airway epithelial cells Ransford et al. (2009)
Tracheal epithelial cells Ransford et al. (2009)
Urinary system Kidney tissue Jeličić et al. (2022)
Bladder urethral cells Negoro et al. (2013)
Proximal tubular cells Su et al. (2019)
Reproductive system Uterus epithelial cells Imamura et al. (2020)
Umbilical vein endothelial cells Lohman et al. (2015)
Circulatory system Red blood cells Rougé et al. (2022)
Macrophages Chen et al. (2019)
Monocytes Parzych et al. (2017), Chen et al. (2019)
Thrombocytes Li et al. (2023), Metz et al. (2023)
T-lymphocytes Boyd-Tressler et al. (2014)