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. 2023 Jul 10;14:1163269. doi: 10.3389/fmicb.2023.1163269

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Copyright © 2023 Liu, Ma, Zhu, Liu, Qin, Lv, Feng, Wang and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The distinct composition and community structure of gut microbiota in 6-week-old and 6-month-old infants. Alpha diversity is shown as the Shannon index (A) and Simpson index (B). (C) Principal coordinates analysis (PCoA) based on Bray–Curtis distance is shown along the first two principal coordinate (PC) axes with Adonis p-value and effect sizes (R²). (D) Comparison of the weighted UniFrac within-group distance of infants. The shorter distance indicated greater similarity in microbial community composition. Boxplots were shown as medians with range. (E) A heatmap of the top 15 bacterial OTUs (average relative abundance >1%) clustered according to age. Values range from low (black) to high (red). A significant difference was determined by Student's t-test (^****p < 0.0001). 6W, 6-weeks-old infants; 6M, 6-months-old infants.