The calculated ΔG (binding free energies) of the synthesized compounds and reference drug against VEGFR-2 TK (ΔG in kcal mol⁻¹).

Comp.	ΔG [kcal mol−1]	Comp.	ΔG [kcal mol−1]
9a	−8.70	12a	−8.95
9b	−8.23	12b	−9.17
9c	−8.95	12c	−8.99
9d	−8.85	12d	−9.01
11a	−9.32	12e	−9.34
11b	−8.82	12f	−8.60
11c	−9.06	12g	−8.90
11d	−9.30	Sorafenib	−8.70
11e	−9.36