TABLE 1.
The IC50 values of PA and cisplatin‐treated A549 and A549/V16 cells.
Cell line | Time | PA | Cisplatin | VCR |
---|---|---|---|---|
A549 | 24 h | 107.84 ± 0.67 | >53.14 | 0.21 ± 0.03 |
48 h | 106.18 ± 6.34 | 22.02 ± 3.39 | 0.04 ± 0.01 | |
A549/V16 | 24 h | 128.94 ± 2.52 | 42.38 ± 1.00 | 0.53 ± 0.03 |
48 h | 125.52 ± 2.92 | 11.99 ± 0.03 | 0.23 ± 0.02 | |
SVEC | 24 h | 158.41 ± 0.48 | 41.65 ± 1.13 | 0.22 ± 0.02 |
48 h | 167.31 ± 4.02 | 10.76 ± 0.27 | 0.05 ± 0.01 |
Note: The half‐maximal inhibitory concentration (IC50) values were calculated from dose–response curves of PA or cisplatin at 24 and 48 h and are presented as mean ± standard deviation (μM) from three independent experiments.
Abbreviations: PA, patchouli alcohol; VCR, vincristine.