REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Human TM4SF4 APC-conjugated Antibody	R&D systems	Cat#FAB7998A
Critical commercial assays
QIAamp DNA Mini Kit	Qiagen	Cat#51304
Nextera XT DNA Library Prep	Illumina	Cat#FC-131-1096
Dual Luciferase Assay System	Promega	Cat#E1500
ANGPTL3 ELISA	R&D Systems	Cat#DANL30
Deposited data
HNF1A function scores	This paper (Table S2)	https://medschool.ucsd.edu/som/medicine/divisions/endocrinology/research/labs/majithia/data/Pages/default.aspx
Experimental models: Cell lines
HUH7	JCRB	JCRB0403
Hep3B	ATCC	HB-8064
Oligonucleotides
HNF1A KO sgRNA (CTGTCCCAACACCTCAACAA)	This paper	N/A
Primers and sequences for functional testing, see Table S11	This paper	N/A
Software and algorithms
ORFcall	Majithia et al.20	https://github.com/tedsharpe/ORFCall
R statistical software v3.5.1	N/A	http://www.R-project.org/
lme4 v1.1-17, lmerTest v3.1-2	N/A	https://github.com/lme4/lme4
SnpEff v4.3	Cingolani et al.84	https://pcingola.github.io/SnpEff/se_introduction/
Kallisto v0.44.0	Bray et al.85	https://pachterlab.github.io/kallisto/
DESeq2 v1.22.1	Love et al.86	http://www.bioconductor.org/packages/release/bioc/html/DESeq2.html
fGSEA v1.8.0	Subramanian et al.55; Mootha et al.56	https://doi.org/10.18129/B9.bioc.fgsea