FIGURE 2.
(A) Enrichment of the T‐cell receptor (TCR)/B‐cell receptor (BCR) pool in clones. There are slight increases in the percentage of unique clones accounting for >0.01% of total TCRs/BCRs before and after radiotherapy, and large increases in that of unique clones accounting for >0.1% of total TCRs/BCRs. (B) Top 10 TCR/BCR clones after radiotherapy. In the TCR repertoire, the top 10 clones are mostly similar to that before radiotherapy, but there are some changes (the percentages of the 1st, 2nd, and 4th clones increased more than 0.5%). In the BCR repertoire, all the top 10 clones before radiotherapy are replaced after radiotherapy. Furthermore, 9 of the 10 clones are newly detected after radiotherapy. □: before radiotherapy; ■: after radiotherapy; *: not detected.