Figure 2.
Characteristics of effect size of DivD-EUR-associated SNPs
(A) Per-effect allele OR vs. effect allele frequency for DivD-EUR-associated SNPs (p < 1.0E−5).
(B) Regression of DivD-SAS and DivD-AFR GWAS SNP effect sizes on DivD-EUR effect sizes of SNPs that are genome-wide significant. Each dot represents an SNP, and labeled SNPs are those with association p value within the corresponding ancestry <0.05. The number in the bracket corresponds to the number in the “#” column of Figure S3. The regression line and 95% CI are presented. Note that rs10910384 (#7) in AFR ancestry was the only significant association (p = 1.4E−06) after Bonferroni correction from these analyses.