Figure 7.

Schematic plot of the mechanism insights from the current DivD GWAS study

The biological insights into the potential mechanisms of genetic predisposition to DivD onset could be summarized into four themes (capitalized words in the four blue triangles with the regional enlarged illustration in the four boxes). Note that the pericytes annotation belongs to the colon structure theme. The italic words represent some of the pathological changes observed in DivD patients and the non-italic non-capitalized words are linked to the meaning of corresponding illustrations using black segments. Detailed descriptions are provided in the Discussion.