Table 2.
Prediction accuracy of PGS in DivD risk in UKB SAS and AFR ancestry participants
Biobank | Ancestry | No. of cases/no. of controls | Logistic regression coefficient | s.e. for logistic regression coefficient | p value for logistic regression coefficient | AUC | 95% CI of AUC | R2 on the liability scale | s.e. for R2 on the liability scale |
---|---|---|---|---|---|---|---|---|---|
UKB | SAS | 760/11,136 | 0.485 | 0.038 | 6.9E−37 | 0.638 | 0.612–0.658 | 0.053 | 0.008 |
AFR | 596/8,579 | 0.320 | 0.043 | 8.9E−14 | 0.587 | 0.563–0.611 | 0.023 | 0.006 | |
CARTaGENEa | EUR | 146/7,550 | 0.708 | 0.085 | 9.7E−17 | 0.688 | 0.645–0.732 | 0.079 | 0.019 |
Results of prediction accuracy of PGS in individuals of EUR ancestry are also listed for comparison.