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. 2023 Jul 10;14:1151870. doi: 10.3389/fimmu.2023.1151870

Table 5.

Univariate linear associations between sequencing quality indicators and maternal and infant characteristics, milk collection timing, and infant feeding characteristics.

Proportion of rRNA Proportion unmapped reads
β (95% CI) P β (95% CI) P
Maternal and infant characteristics
Mother age (years) -0.0003 (-0.002, 0.001) 0.72 0.004 (-0.0002, 0.007) 0.06
Socioeconomic status -0.0004 (-0.001, 0.0004) 0.31 0.0001 (-0.002, 0.002) 0.88
Pre-pregnancy BMI (kg/m2) 0.0008 (-0.001, 0.003) 0.42 -0.004 (-0.008, -0.003 0.04
Maternal BMI (kg/m2) 0.0003 (-0.002, 0.002) 0.78 -0.004 (-0.009, -0.00002) 0.049
Infant sex 0.02 (-0.003, 0.04) 0.10 -0.02 (-0.07, 0.02) 0.30
Mode of delivery 0.003 (-0.02, 0.03) 0.77 -0.02 (-0.07, 0.03) 0.46
Days postpartum 0.0003 (-0.003, 0.003) 0.82 -0.0003 (-0.007, 0.006) 0.92
Gestational age
Breast milk collection timing
Season (ref = cold) 0.01 (-0.006, 0.03) 0.16 -0.01 (-0.05, 0.03) 0.65
Breast milk collection time (hours past midnight) -0.003 (-0.01, 0.003) 0.30 -0.02 (-0.03, -0.003) 0.02
Infant feeding characteristics
Predominantly breastfed -0.003 (-0.02, 0.02) 0.73 0.02 (-0.02, 0.01) 0.27
Breastfeedings per day -0.002 (-0.006, 0.002) 0.29 0.002 (-0.007, 0.01) 0.67

Beta coefficients and 95% confidence intervals (CI) from univariate linear regression analysis used to examine the associations between sequencing quality indicators and maternal and infant characteristics, milk collection timing, and infant feeding characteristics. P-values in bold denote statistical significance for P or PFDR < 0.05.