Table 5.
Univariate linear associations between sequencing quality indicators and maternal and infant characteristics, milk collection timing, and infant feeding characteristics.
| Proportion of rRNA | Proportion unmapped reads | |||
|---|---|---|---|---|
| β (95% CI) | P | β (95% CI) | P | |
| Maternal and infant characteristics | ||||
| Mother age (years) | -0.0003 (-0.002, 0.001) | 0.72 | 0.004 (-0.0002, 0.007) | 0.06 |
| Socioeconomic status | -0.0004 (-0.001, 0.0004) | 0.31 | 0.0001 (-0.002, 0.002) | 0.88 |
| Pre-pregnancy BMI (kg/m2) | 0.0008 (-0.001, 0.003) | 0.42 | -0.004 (-0.008, -0.003 | 0.04 |
| Maternal BMI (kg/m2) | 0.0003 (-0.002, 0.002) | 0.78 | -0.004 (-0.009, -0.00002) | 0.049 |
| Infant sex | 0.02 (-0.003, 0.04) | 0.10 | -0.02 (-0.07, 0.02) | 0.30 |
| Mode of delivery | 0.003 (-0.02, 0.03) | 0.77 | -0.02 (-0.07, 0.03) | 0.46 |
| Days postpartum | 0.0003 (-0.003, 0.003) | 0.82 | -0.0003 (-0.007, 0.006) | 0.92 |
| Gestational age | ||||
| Breast milk collection timing | ||||
| Season (ref = cold) | 0.01 (-0.006, 0.03) | 0.16 | -0.01 (-0.05, 0.03) | 0.65 |
| Breast milk collection time (hours past midnight) | -0.003 (-0.01, 0.003) | 0.30 | -0.02 (-0.03, -0.003) | 0.02 |
| Infant feeding characteristics | ||||
| Predominantly breastfed | -0.003 (-0.02, 0.02) | 0.73 | 0.02 (-0.02, 0.01) | 0.27 |
| Breastfeedings per day | -0.002 (-0.006, 0.002) | 0.29 | 0.002 (-0.007, 0.01) | 0.67 |
Beta coefficients and 95% confidence intervals (CI) from univariate linear regression analysis used to examine the associations between sequencing quality indicators and maternal and infant characteristics, milk collection timing, and infant feeding characteristics. P-values in bold denote statistical significance for P or PFDR < 0.05.