Table 3.
No. | Relapse time | Relapse sites | Main treatment | Effect | Outcome |
---|---|---|---|---|---|
P1 | 3 m+ | Bone marrow | Treatment abandoning | – | Death |
P2 | 4 m+ | Bone marrow, testiclesskin | DLI, Treatment abandoning | – | Death |
P3 | 4 m+ | Myeloid sarcoma | Secondary HSCT | Second relapse of myeloid sarcoma | Death |
P4 | 5 m+ | Bone marrow, mesentery, submandibular gland | Treatment abandoning | – | Death |
P5 | 15 m+ | Bone marrow (molecular biology) | Secondary HSCT | Sustained CR, MRD Fluctuation, given DLI again | Survival |
P6 | 22 m+ | CNS | Secondary HSCT | CNS (–) | Survival |
P7 | 26 m+ | Bone marrow (molecular biology) | DLI | Sustained CR, MRD Fluctuation | Survival |
P8 | 35 m+ | Bone marrow | Secondary HSCT | Sustained CR | Survival |
P9 | 46 m+ | Bone marrow (molecular biology) | Secondary HSCT | Sustained CR, MRD (–) | Survival |
CNS: central nervous system; CR: complete remission; DLI: donor lymphocyte infusion; HSCT: hematopoietic stem cell transplantation; m: month; MRD: minimal residual disease; Relapse time: from the day of stem cell infusion.