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. 2023 May 4;21(8):1560–1576. doi: 10.1111/pbi.14057

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© 2023 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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A proposed mechanism model of ‘MdRAD23D1‐MdPRP6’ regulon in apples under drought. Under drought stress, MdRAD23D1 protein levels increase, accelerating MdPRP6 degradation via 26S proteasome, there by the MdPRP6 protein levels decrease under drought. The free proline from MdPRP6 degradation might contribute to build up a high cellular free proline content. In addition, MdPRP6 affects the P5CS activity, might via the ABA pathway, to regulate proline synthesis. The increased free proline then makes apple plants resist drought stress.