Table 2.
Available metabolism studies
| Primary crops | Crop groups | Crop(s) | Application(s) | Sampling (DAT) | Comment/source |
|---|---|---|---|---|---|
| Fruit crops | Apple | Foliar (spray appl.), Total seasonal rate of 80–200 g a.s./ha in 11 (a) appl., 1–2 weeks intervals between treatments | 6 h, 29, 49 DALT | [14C‐carbinol]‐fenarimol (FAO and WHO, 1995, 1996; UK, 1996; EFSA, 2011) | |
| Post‐harvest (mist spray appl.), 1 mL of formulated product/apple eq. to 8.93 g a.s./kg of apples | 14 | 2 studies: [14C‐carbinol]‐fenarimol and mixture of [14C‐carbinol], [14C‐4‐chlorophenyl] and [14C‐2‐chlorophenyl]‐fenarimol (FAO and WHO, 1995, 1996; UK, 1996; EFSA, 2011) | |||
| Grapes | Foliar (spray appl.), total seasonal rate of 166 g a.s./ha in 4 appl. (2 weeks intervals between treatments) or 1 × 500 mg/L formulation (dose unspecified) | 0, 15, 30, 45, 60 | Mixture of [14C‐carbinol], [14C‐4‐chlorophenyl] and [14C‐2‐chlorophenyl]‐fenarimol (FAO and WHO, 1995, 1996; UK, 1996; EFSA, 2011) | ||
| Cucumber | Foliar (spray appl.), 1 × 24.7 g a.s./ha | 4 | [14C‐carbinol]‐fenarimol (FAO and WHO, 1995, 1996; UK, 1996; EFSA, 2011) | ||
| Root crops | – | – | – | No study available | |
| Leafy crops | – | – | – | No study available | |
| Cereals/grass | – | – | – | No study available | |
| Pulses/oilseeds | – | – | – | No study available |
| Livestock | Animal | Dose (mg/kg DM/day) | Duration (day) | Comment/source |
|---|---|---|---|---|
| Chicken | 0.7 or 7 | 5 | [14C‐carabinol] (FAO and WHO, 1995, 1996; UK, 1996) | |
| Laying hens | 0.6 | 7 days, then 23 days of epuration |
[14C‐carabinol] (FAO and WHO, 1995, 1996; UK, 1996) Only eggs were analysed |
|
| Ruminant, goat | 2 × 10 | 5 | [14C‐carbinol] (FAO and WHO, 1995, 1996; UK, 1996) | |
| Pigs | 2 × 1 | 5 | 1 pig with [14C‐carbinol], 1 with [14C‐2‐chlorophenyl] and 1 with [14C‐4‐chlorophenol] (FAO and WHO, 1995, 1996; UK, 1996) |
a.s.: active substance; DAT: days after treatment; DALT: days after last treatment; DM: dry matter.
(a)
The first application out of 11 is conducted with non‐radiolabelled active substance.