Table 4.
Analytical methods available
| Commodity group | Analytical method available | LOQ (mg/kg) | Source | |
|---|---|---|---|---|
| Plant commodities | High water content | Yes (methanol or another hydrophilic solvent system for extraction; GC‐ECD) | 0.01 |
UK (1996) EFSA (2011) |
| Yes (QuEChERS method with LC‐MS/MS) | 0.01 | EFSA (2011) | ||
|
Yes (QuEChERS method with GC‐MS/MS) |
0.01 | EURLs (2022) | ||
| High oil content | Yes (QuEChERS and QuOil method with GC‐MS/MS) | 0.01 | EURLs (2022) | |
| High acid content | Yes (methanol or another hydrophilic solvent system for extraction; GC‐ECD) | 0.01 |
UK (1996) EFSA (2011) |
|
| Yes (QuEChERS method with LC‐MS/MS) | 0.01 | EFSA (2011) | ||
|
Yes (QuEChERS method with GC‐MS/MS) |
0.01 | EURLs (2022) | ||
| Dry |
Yes (QuEChERS method with GC‐MS/MS and LC‐MS/MS) |
0.01 | EURLs (2022) | |
| Animal commodities | Muscle | Yes (methanol/acetonitrile or methanol/methylene chloride extraction; extracts cleaned up on a Florisil column; analysis with GC‐ECD) | 0.01 |
UK (1996) |
| Yes (Q‐EMR method with GC‐MS/MS) | 0.01 | EURLs (2022) | ||
| Kidney | Yes (GC‐ECD) | 0.01 |
UK (1996) |
|
| – | 0.01 (a) | EURLs (2022) | ||
| Liver | Yes (GC‐ECD) | 0.01 |
UK (1996) |
|
| Yes (Q‐EMR method with GC‐MS/MS) | 0.01 | EURLs (2022) | ||
| Fat | Yes (hexane/1‐chlorobutane extraction; extracts cleaned up on a Florisil column; analysis with GC‐ECD) | 0.01 |
UK (1996) |
|
| – | 0.01 (a) | EURLs (2022) | ||
| Milk | Yes (acetonitrile extraction then washed with hexane and partitioned with methylene chloride; extracts cleaned up on a Florisil column; analysis with GC‐ECD) | 0.01 |
UK (1996) |
|
| – | 0.01 (a) | EURLs (2022) | ||
| Eggs | Yes (methanol/acetonitrile or methanol/methylene chloride extraction; extracts cleaned up on a Florisil column; analysis with GC‐ECD) | 0.01 |
UK (1996) |
|
| Yes (Q‐EMR method with GC‐MS/MS or GC‐Orbitrap) | 0.01 | EURLs (2022) | ||
| Fish | Yes (Q‐EMR method with GC‐MS/MS) | 0.01 | EURLs (2022) | |
LOQ: limit of quantification; GC‐ECD: gas chromatography with electron capture detector; GC‐MS/MS: gas chromatography with tandem mass spectrometry; LC‐MS/MS: liquid chromatography with tandem mass spectrometry; QuEChERS: Quick, Easy, Cheap, Effective, Rugged and Safe (analytical method); Q‐EMR: QuEChERS with Enhanced Matrix Removal.
Although no validation data are available for this specific commodity within the EURLs, it is assumed that the reported LOQ would be achievable based on the experience gained with fenarimol in other matrices.