Table 6.

Toxicological reference values (TRVs) set at EU level

TRV	Value	Reference	Comments
ADI	0.01 mg/kg bw per day	European Commission (2007)	Based on the NOAEL of 1.3 mg/kg bw per day for reduced body weight gain, increase in fatty liver and hyperplastic liver nodules observed at 2.47 mg/kg bw per day in a 2‐year study in rats and applying an UF of 100
ARfD	0.02 mg/kg bw	European Commission (2007)	Based on a NOAEL for fertility of 2 mg/kg bw per day and applying and UF of 100

ADI: acceptable daily intake; ARfD: acute reference dose; bw: body weight; NOAEL: no observed adverse effect level; UF: uncertainty factor.